Some medications : Several gastrointestinal, digestive, sleep, and mood medications have links with collagenous colitis.
antidepressants, including selective serotonin reuptake inhibitorsĪlthough people of any age can develop collagenous colitis, factors that may increase the risk of the condition include:.proton pump inhibitors, including lansoprazole (Prevacid) and omeprazole (Prilosec).nonsteroidal anti-inflammatories (NSAIDs), such as ibuprofen, naproxen, and aspirin.Some of the medications that have common associations with the development of collagenous colitis include: bacterial, viral, and fungal infections.autoimmune conditions, such as celiac disease, Graves’ disease, Crohn’s disease, ulcerative colitis, Hashimoto’s thyroiditis, rheumatoid arthritis, and psoriasis.Some of the proposed causes of collagenous colitis include: Most research indicates it likely has a genetic basis and may have links with other autoimmune diseases. In cases of collagenous colitis, the layer of collagen - the connective tissue protein that helps support the epithelial cells - becomes thicker than expected.Ĭollagenous colitis is similar to many other inflammatory gastrointestinal conditions, and researchers are not sure why the condition occurs. When colon epithelial cells become damaged, a variety of digestive symptoms occur. The colon takes a liquid mixture of digested food from the small intestine and turns it into a solid stool before delivering it to the rectum for removal from the body.Ĭollagenous colitis causes general inflammation of the epithelium, the base layer of cells that line the colon.Ĭolon epithelial cells are vital to the organ’s overall performance because they help digestion and maintain the relationship between the body’s immune system and the healthy communities of microbes in the gut. If you have not already, please report the rash to your doctor so they may evaluate the cause.Collagenous colitis affects the colon, which is the large intestine. In fact, that is the most common adverse event reported when therapy with the drug is discontinued. The rashes that occur on Lamictal therapy may be mild but they can also be extremely serious. In regard to Lamictal, it can cause rashes and hypersensitivity reactions. So, while an allergic reaction to Metamucil is uncommon, it can't be ruled out. Below is a picture of the ingredients contained in one particular Metamucil product: Metamucil also contains additional ingredients as well, not just psyllium. Due to the prevalent usage of psyllium powder in many health care facilities, it has been found that airborne powder can exacerbate asthma as well as cause sensitivity reactions, simply by inhalation.
In fact, psyllium powder is listed as an occupational allergen in many institutions. It is certainly possible that you have a sensitivity to it as well. There are a multitude of case reports and studies that indicate there is a portion of the population that does indeed have a sensitivity to psyllium. Although Metamucil is generally well tolerated and has a long history of safe and effective use, it is well known that psyllium can cause allergic reactions in those sensitive to it. It is a naturally sourced product that comes from the outer husk of the psyllium seed ( Plantago psyllium). The type of fiber used in Metamucil products is psyllium. Would Metamucil be the issue I got? AnswerĪs with any drug, dietary supplement or natural product, an allergic reaction is possible if you have a sensitivity to a certain ingredient. The next morning I got a itching rash on my face and swelling. I drank Metamucil and waited 3 hours, then took Lamictal tablets.
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